| Biography | |
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 Prof. Lin Liu Oklahoma State University, USA |
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| Title: Role of non-coding RNAs in the pathogenesis of lung diseases | |
| Abstract:
Although the majority of the mammalian genome has beentranscribed, less than 2% of the transcripts encode proteins. Non-coding RNAs have been increasingly recognized for their importance in regulating various biological processes. Non-coding RNAs are classified as small non-coding RNAs with 20-30 nucleotides such as microRNAs and long non-coding RNAs (lncRNAs) with a size of > 200 nucleotides.While microRNAs mainly control gene expression at the post-transcriptional level, lncRNAs act by interacting with RNA, DNA and protein to activate or repress gene expression at various levels, including transcription, splicing, mRNA stability, and translation. This talk will discuss strategies to identify non-coding RNAs involved in lung diseases and follow-up functional and mechanistic studies of the identified non-coding RNAs.
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| Biography: Dr. Lin Liu received his BS from University of Science and Technology of China in 1984 and his PhD from Shanghai Institute of Biochemistry, Chinese Academy of Sciences in 1989. He did his postdoctoral training at University of Pennsylvania, USA from 1990. Dr. Liu had his first faculty appointment at East Carolina University in 1997and joined Oklahoma State University (OSU) as Associate Professor of Physiological Sciences in 2000. He was promoted to tenured Full Professor in 2004, and appointed to Lundberg-Kienlen Endowed Professor/Chair in Biomedical Research in 2008 and Regents Professor in 2009. Dr. Liu was selected as a Riata Faculty Fellow in the OSU School of Entrepreneurship in 2010. He is Founding Director of the Oklahoma Center for Respiratory and Infectious Diseases and the Interdisciplinary Program in Regenerative Medicine at OSU. Dr. Liu has also directed the Lung Biology and Toxicology Laboratory since 2000. His current research interests are development of drugs targeting host factors for treating influenza virus infection, adult stem cell therapy of COPD and pathogenesis of pulmonary fibrosis. Dr. Liu has received over 34 million in grants from federal agencies (National Institutes of Health and U.S. Department of Agriculture), foundations (American Heart Association and March of Dimes) and other local agencies. Dr. Liu has also served on grant review panels for the NIH, Chinese National Science Foundation and many other granting entities. He has served as Chair of the OSU Biomedical Sciences Group of the Graduate Faculty Council. Dr. Liu has been a member of the Steering Committee for the Physiological Genomics Interest Group of the American Physiological Society. Dr. Liu has a long track record in training and mentoring rising scientists. He has trained over 50 postdoctoral fellows and graduate students and published over 110 papers. Dr. Liu has received several awards including the Pfizer Award for Research Excellence twice and the OSU Regents Distinguished Research Award. | |
