Prof. Hyun-Min Kim_GECT 2024

Biography
Prof. Hyun-Min Kim Duke Kunshan University, China
Abstract: CRISPR-Cas technology has ushered in a new era of genome editing, offering unprecedented precision and efficiency. Its versatility extends across various domains, aided by the contributions of model organisms like C. elegans. However, the abundance of CRISPR-Cas methods presents a challenge in selecting the most suitable approach. In this talk, I will overview the applications of CRISPR-Cas in C. elegans, exploring key strategies and features. By elucidating significant advancements, I aim to provide a comprehensive understanding of the current state of genome editing and empower attendees to seamlessly navigate the multitude of CRISPR-Cas techniques.
Biography: Dr. Kim's illustrious research career is distinguished by his unwavering commitment to unraveling the intricate mechanisms of DNA damage repair and genome editing. His journey began with a fervent dedication to understanding the fundamental processes underlying DNA repair pathways, which are pivotal for maintaining genome integrity. Throughout his academic endeavors, Dr. Kim has emerged as a pioneering figure in this field, leveraging his expertise to develop innovative methodologies and advance scientific knowledge. A significant milestone in Dr. Kim's research trajectory was the development of a streamlined method for CRISPR-Cas genome editing in C. elegans, a groundbreaking achievement that revolutionized genetic manipulation techniques in this model organism. His methodological innovation enabled precise genome modifications, including the introduction of mutations, epitopes, and deletions, with unprecedented efficiency and accuracy. Furthermore, Dr. Kim's pioneering work extended beyond method development, as he generated transgenic worms for research purposes, expanding the toolkit available for genetic studies in C. elegans. Dr. Kim's contributions to genome editing have not only facilitated novel avenues of research but have also shed light on the intricate processes underlying DNA damage repair. By elucidating the molecular mechanisms governing DNA repair pathways, Dr. Kim has provided invaluable insights into the cellular responses to genotoxic stress and the maintenance of genome stability. His research has uncovered the role of epigenetic modifiers in DNA repair processes, highlighting the intricate interplay between chromatin remodeling and DNA damage response. Beyond his groundbreaking research endeavors, Dr. Kim has also made significant contributions to the academic community through his teaching and mentorship activities. As a former professor at Tianjin University and currently serving at Duke Kunshan University, Dr. Kim has imparted knowledge and fostered the intellectual growth of countless students. His instructional journey has been characterized by innovative teaching strategies and a commitment to excellence in education. Dr. Kim's influence extends beyond the confines of the classroom, as he actively engages in collaborative research projects with his students, resulting in impactful contributions to the field of biology. His collaborative efforts have led to significant advancements in CRISPR-Cas genome editing and the exploration of anti-cancer drug effects on reproduction and meiosis. Through these collaborative endeavors, Dr. Kim has nurtured the next generation of scientists, instilling in them a passion for scientific inquiry and a commitment to excellence.

Biography

Prof. Hyun-Min Kim
Duke Kunshan University, China

Abstract:
CRISPR-Cas technology has ushered in a new era of genome editing, offering unprecedented precision and efficiency. Its versatility extends across various domains, aided by the contributions of model organisms like C. elegans. However, the abundance of CRISPR-Cas methods presents a challenge in selecting the most suitable approach. In this talk, I will overview the applications of CRISPR-Cas in C. elegans, exploring key strategies and features. By elucidating significant advancements, I aim to provide a comprehensive understanding of the current state of genome editing and empower attendees to seamlessly navigate the multitude of CRISPR-Cas techniques.

Biography:

Dr. Kim's illustrious research career is distinguished by his unwavering commitment to unraveling the intricate mechanisms of DNA damage repair and genome editing. His journey began with a fervent dedication to understanding the fundamental processes underlying DNA repair pathways, which are pivotal for maintaining genome integrity. Throughout his academic endeavors, Dr. Kim has emerged as a pioneering figure in this field, leveraging his expertise to develop innovative methodologies and advance scientific knowledge.

A significant milestone in Dr. Kim's research trajectory was the development of a streamlined method for CRISPR-Cas genome editing in C. elegans, a groundbreaking achievement that revolutionized genetic manipulation techniques in this model organism. His methodological innovation enabled precise genome modifications, including the introduction of mutations, epitopes, and deletions, with unprecedented efficiency and accuracy. Furthermore, Dr. Kim's pioneering work extended beyond method development, as he generated transgenic worms for research purposes, expanding the toolkit available for genetic studies in C. elegans.

Dr. Kim's contributions to genome editing have not only facilitated novel avenues of research but have also shed light on the intricate processes underlying DNA damage repair. By elucidating the molecular mechanisms governing DNA repair pathways, Dr. Kim has provided invaluable insights into the cellular responses to genotoxic stress and the maintenance of genome stability. His research has uncovered the role of epigenetic modifiers in DNA repair processes, highlighting the intricate interplay between chromatin remodeling and DNA damage response.

Beyond his groundbreaking research endeavors, Dr. Kim has also made significant contributions to the academic community through his teaching and mentorship activities. As a former professor at Tianjin University and currently serving at Duke Kunshan University, Dr. Kim has imparted knowledge and fostered the intellectual growth of countless students. His instructional journey has been characterized by innovative teaching strategies and a commitment to excellence in education.

Dr. Kim's influence extends beyond the confines of the classroom, as he actively engages in collaborative research projects with his students, resulting in impactful contributions to the field of biology. His collaborative efforts have led to significant advancements in CRISPR-Cas genome editing and the exploration of anti-cancer drug effects on reproduction and meiosis. Through these collaborative endeavors, Dr. Kim has nurtured the next generation of scientists, instilling in them a passion for scientific inquiry and a commitment to excellence.